Tetsuo Ashizawa, M.D.
Chairman
The Melvin Greer Professor of Neurology

Phone: (352) 273-5550
Fax: (352) 273-5575
tetsuo.ashizawa@neurology.ufl.edu

Department of Neurology
L3-100 McKnight Brain Institute
Newell Drive
Gainesville, FL. 32610

Professional Background:
M.D., Keio University School of Medicine, Tokyo, Japan (1973)

Personal Info
Dr. Ashizawa completed his Neurology residency training at Baylor College of Medicine where he was appointed Chief Neurology Resident. He then completed fellowship training in Neuromuscular Studies and Neurochemistry with the Muscular Dystrophy Association at Baylor.

Research Interests
Spinocerebellar Ataxia Sub-type 10
Myotonic Dystrophy Type 1
Huntington’s Disease
Friedreich’s Ataxia
Parkinson's Disease
Myasthenia Gravis

Selected Peer-Reviewed publications (in chronological order)
(Publications selected from 127 peer-reviewed papers, 7 invited editorials, 14 invited reviews, 27 book chapters, 1 book, and 7 electronic journal publications).

1. Fu Y-H, Pizzuti A, Fenwick R, King J, Rajnarayan S, Dunne PW, Dubel J, Nasser GA, Ashizawa T, de Jong P, Wieringa B, Korneluk R, Perryman MB, Epstein HF, Caskey CT. An unstable triplet repeat in a gene related to myotonic muscular dystrophy. Science 1992;225:1256-1258

2. Fu Y-H, Friedman DL, Richards S, Pearlman JA, Gibbs RA, Pizzuti A, Ashizawa T, Perryman MB, Scarlato G, Fenwick RG, Jr, Caskey CT. Decreased expression of myotonin-protein kinase messenger RNA and protein in adult form of myotonic dystrophy. Science 1993;260:235-238

3. Ashizawa T, Anvret M, Baiget M, Barceló JM, Brunner H, Cobo AM, Dallapiccola B, Fenwick RG Jr, Grandell U, Harley H, Junien C, Koch MC, Korneluk RG, Lavedan C, Miki T, Mulley JC, López de Munain A, Novelli G, Roses AD, Seltzer WK, Shaw DJ, Smeets H, Sutherland GR, Yamagata H, Harper PS. Characteristics of intergenerational contractions of the CTG repeat in myotonic dystrophy. Am J Hum Genet 1994;54:414-423

4. Fu Y-H, Pearlman JA, Pizzuti A, Fenwick RG, Friedman DL, Perryman MB, Richards S, Gibbs RA, Ashizawa T, Scarlato G, Caskey CT. Muscle biochemistry and a genetic study of myotonic dystrophy. Science 1994;264:587-588

5. Tokgozoglu LS, Ashizawa T, Pacifico A, Epstein H, Zoghbi WA. Cardiac involvement in a large kindred with myotonic dystrophy:quantitative assessment and relation to expansion of CTG repeats. JAMA 1995;274:813-819

6. Zhuchenko O, Bailey J, Bonnen P, Ashizawa T, Stockton DW, Amos C, Dobyns WB, Subramony SH, Zoghbi HY, Lee CC. Autosomal dominant cerebellar ataxia (SCA6) associated with small polyglutamine expansions in the ??1A-voltage-dependent calcium channel. Nature Genet 1997;15:62-69

7. Matsuura, T., Yamagata, T., Burgess, D.L., Rasmussen, A., Grewal, R.P., Watase, K., Khajavi, M., McCall, A., Caleb F. Davis, C.F., Zu, L., Achari, M., Pulst, S.M., Alonso, E., Noebels, J.L., Nelson, D.L., Zoghbi, H.Y., Ashizawa, T. Large Expansion of ATTCT Pentanucleotide Repeat in Spinocerebellar Ataxia Type 10. Nat Genet 2000;26:191-194

8. Matsuura T, Fang P, Lin X, Khajavi M, Tsuji K, Rasmussen A, Grewal RP, Achari M, Alonso ME, Pulst SM, Zoghbi HY, Nelson DL, Roa BB, Ashizawa T. Somatic and germline instability of the ATTCT repeat in spinocerebellar ataxia type 10. Am J Hum Genet 2004:74;1216-1224.

9. Subramony SH, May W, Lynch D, Gomez C, Fischbeck K, Hallett M, Taylor P, Wilson R, Ashizawa T; Cooperative Ataxia Group. Measuring Friedreich ataxia: Interrater reliability of a neurologic rating scale. Neurology 2005;64:1261-1262.

10. Gatto EM, Gao R, White MC, Uribe Roca MC, Etcheverry JL, Persi G, Poderoso JJ, Ashizawa T. Ethnic origin and extrapyramidal signs in an Argentinean spinocerebellar ataxia type 10 family. Neurology 2007; 69:216-218.